Association of distal chromosome 2q with IDDM in Japanese subjects
نویسندگان
چکیده
منابع مشابه
Association of two loci on chromosome 2q with nodal osteoarthritis.
OBJECTIVE To search for genetic association between microsatellite marker loci and sibling pairs with nodal osteoarthritis (NOA). METHODS Using the affected sibling pair method of analysis, genomic DNA from 66 sib pairs with NOA was analysed for association with highly polymorphic microsatellite marker loci. The microsatellite markers were amplified using polymerase chain reaction and typed o...
متن کاملFamily association studies of markers on chromosome 2q and Type 1 diabetes in subjects from South India.
BACKGROUND Several Type 1 diabetes susceptibility loci have been located to chromosome 2q12-21. However, results have not always been consistent and this may reflect study design and the population analysed. We have used a family-based design to look for an association between Type 1 diabetes and markers located to 2q12-21. METHODS Ninety-one South Indian families consisting of subjects with ...
متن کاملLinkage analysis of chromosome 2q in osteoarthritis.
BACKGROUND In independent linkage studies chromosome 2q11-q24 and chromosome 2q23-35 have previously been implicated as regions potentially harbouring susceptibility loci for osteoarthritis (OA). OBJECTIVE To test chromosome 2q for linkage to idiopathic osteoarthritis. METHODS Using a cohort of 481 OA families that each contained at least one affected sibling pair with severe end-stage dise...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation between high serum total IgE levels and D11S97 on chromosome 11q13 in Japanese subjects.
The genetic linkage of atopy to chromosome 11q13 through maternally derived alleles has been previously reported. Linkage analysis in Japanese families did not confirm the existence of a major gene for atopy at this locus under the model of autosomal dominant inheritance. However, we observed a significant association between serum total IgE levels and genetic markers at this locus both in 14 J...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1998
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s001250050894